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Updated: Mar 17, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Interdisciplinary differential treatment of structural heart disease : When operation and when catheter-based
S Yücel1, H Ince2,3,4, S Kische1,5
1Herzzentrum, Med. Klinik I - Kardiologie, Universitätsmedizin Rostock, Ernst-Heydemann-Straße 6, 18057, Rostock, Deutschland.
Insights
Minimally invasive options are crucial for elderly patients with aortic valve stenosis and mitral regurgitation due to high surgical risks. Advances in transcatheter aortic valve implantation (TAVI) and new mitral valve devices offer improved outcomes and expanded treatment possibilities.
Area of Science:
- Cardiology
- Interventional Cardiology
- Geriatric Medicine
Background:
- Societal demographic shifts increase the prevalence of aortic valve stenosis and mitral regurgitation.
- An aging population presents with higher rates of multimorbidity, leading to increased surgical risk and contraindications for traditional surgery.
- Minimally invasive therapeutic options are becoming increasingly vital for managing these complex patient groups.
Purpose of the Study:
- To review the current landscape and future directions of minimally invasive treatments for aortic valve stenosis and mitral regurgitation.
- To highlight the importance of a multidisciplinary heart team approach in optimizing patient selection and therapeutic success.
- To discuss the impact of next-generation transcatheter aortic valve implantation (TAVI) systems and emerging mitral valve devices.
Main Methods:
- Review of current literature on minimally invasive cardiac procedures.
- Analysis of trends in transcatheter aortic valve implantation (TAVI) and novel mitral valve device development.
- Emphasis on the role of multidisciplinary heart teams in patient management.
Main Results:
- Transcatheter aortic valve implantation (TAVI) systems are evolving, promising better outcomes, reduced complications, and lower mortality.
- There is a clear trend towards expanding indications for TAVI.
- Innovative minimally invasive mitral valve devices are in clinical trials, poised to shape future therapeutic strategies.
Conclusions:
- Minimally invasive approaches, particularly TAVI, are expanding treatment options for high-risk patients with aortic and mitral valve disease.
- Continued innovation in device technology and a collaborative heart team approach are essential for improving patient care.
- Future therapies will likely involve further refinement of minimally invasive techniques for both aortic and mitral valve conditions.
Abstract:
The demographic changes in society lead to an increasing number of patients with aortic valve stenosis and mitral regurgitation. Simultaneously the higher age of patients is associated with an increase in multimorbidity with a high surgical risk so that they cannot be referred to surgery. Besides the current gold standard of surgery, minimally invasive therapeutic options are increasingly becoming established for these patients. For the differentiated indications and therapeutic success, a multidisciplinary heart team assumes an important role. The next generation of transcatheter aortic valve implantation (TAVI) systems will lead to improvement in the results, lower complication rates and mortality and as a result there is a general trend towards expanding the indications. New innovative minimally invasive mitral valve devices are still undergoing clinical trials and will define future therapy options.
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