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Concurrent hyperthyroidism and papillary thyroid cancer: a fortuitous and ambiguous case report from a resource-poor
Benjamin Momo Kadia1, Christian Akem Dimala2,3, Ndemazie Nkafu Bechem4
1Presbyterian General Hospital Acha-Tugi, Acha-Tugi, North West Region, Cameroon.
BMC Research Notes
|July 28, 2016
Summary
This case study highlights a rare instance of hyperthyroidism caused by papillary thyroid cancer (PTC) in a Cameroonian woman. Prompt diagnosis and treatment led to a successful outcome, emphasizing the importance of evaluating thyroid nodules.
Area of Science:
- Endocrinology
- Oncology
- Case Study
Background:
- Concurrent thyroid cancer (TC) and hyperthyroidism (HT) is uncommon but increasingly recognized.
- Hyperthyroidism secondary to TC is exceptionally rare, posing significant challenges, particularly in regions like Africa with high TC and HT case fatality rates.
Purpose of the Study:
- To report a rare case of hyperthyroidism caused by papillary thyroid cancer (PTC).
- To emphasize the importance of a high index of suspicion and systematic evaluation of thyroid nodules, especially in resource-limited settings.
Main Methods:
- A 37-year-old female presented with symptoms suggestive of HT and was found to have a left thyroid nodule.
- Initial management included propranolol and methimazole, followed by left thyroid lobectomy.
- Histopathology confirmed papillary thyroid cancer as the cause of HT.
Main Results:
- The patient's hyperthyroid symptoms regressed postoperatively.
- The case demonstrated a positive outcome despite the rarity of the condition and resource limitations.
Conclusions:
- Hyperthyroidism can be caused by papillary thyroid cancer, necessitating careful evaluation of all thyroid nodules.
- Prompt referral and management are crucial for favorable outcomes in rare endocrine-neoplastic conditions.
- This case underscores the importance of systematic diagnostic approaches in resource-poor settings.
