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Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
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COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Bone Disorders01:29

Bone Disorders

6.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
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[COPD and bone].

Ryo Okazaki1

  • 1Third Department of Medicine, Teikyo University Chiba Medical Center, Japan.

Clinical Calcium
|July 28, 2016
PubMed
Summary
This summary is machine-generated.

Chronic obstructive pulmonary disease (COPD) frequently co-occurs with osteoporosis, a condition affecting up to 80% of patients, yet remains largely undiagnosed and untreated due to low awareness.

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Area of Science:

  • Pulmonary Medicine
  • Bone Metabolism
  • Systemic Comorbidities

Background:

  • Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease.
  • Osteoporosis is a common comorbidity in COPD patients, with up to 80% prevalence of vertebral fractures reported.
  • Low awareness of osteoporosis in COPD patients leads to undertreatment.

Purpose of the Study:

  • To highlight the significant prevalence of osteoporosis in COPD patients.
  • To underscore the need for increased awareness and research into the pathophysiology of COPD-associated osteoporosis.

Main Methods:

  • Review of existing literature on COPD and osteoporosis.
  • Identification of shared risk factors and potential pathophysiological links.

Main Results:

  • Osteoporosis is highly prevalent in COPD patients, with high rates of vertebral fractures.
  • Multiple risk factors for osteoporosis are common in COPD, including smoking, low body weight, systemic inflammation, vitamin D insufficiency, and hypoxia.

Conclusions:

  • Osteoporosis is a critical, often overlooked, comorbidity in COPD.
  • Increased clinical awareness and further research into the underlying mechanisms are urgently required for effective patient management.