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Updated: Mar 17, 2026
Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Lac dye as a potential anti-neoplastic agent
Gulsaz Shamim1, Sanjeev Kumar Ranjan2, Dev Mani Pandey3
1Department of Biotechnology, Birla Institute of Technology, Mesra; Lac Production Division, Indian Institute of Natural Resins and Gums, Namkum, Ranchi, Jharkhand, India.
Objective:
Certain anthraquinone compounds are effectively used for treatment of cancer. The present study describes the inhibitory activity of lac dye, a mixture of polyhydroxy anthraquinone compounds (Laccaic acid A, B, C, D and E), produced by the Indian lac insect, Kerria lacca (Kerr).
Materials And Methods:
In vitro testing for anticancer activity of lac dye was done at four concentrations (10, 20, 40, 80 μg/ml) on ten human malignant cell lines including six human leukemia cell lines, U973, Raji, K562, Jurkat, MOLT 4 and HL60 using SRB assay.
Results And Conclusion:
Both crimson and yellow lac dye inhibits proliferation of Human leukemia cell lines, Raji, U937, K562, HL60 and Jurkat, therefore can be considered as a potential anticancer agent for leukemia.
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