Related Experiment Video

Updated: Mar 17, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

12.2K

The Effect of Antiplatelet Agents on Bleeding-Related Complications After Ureteroscopy

Mary E Westerman1, Vidit Sharma1, Joseph Scales1

  • 11 Department of Urology, Mayo Clinic , Rochester, Minnesota.

Journal of Endourology
|July 28, 2016
PubMed

Insights

Continuing antiplatelet therapy (APT) during routine ureteroscopy (URS) is safe. This study found no increased risk of bleeding complications for patients who continued APT, supporting current AUA guidelines.

Area of Science:

  • Urology
  • Cardiovascular Medicine
  • Surgical Complications

Background:

  • Current American Urological Association (AUA) guidelines suggest continuing anticoagulation and antiplatelet therapy (APT) during routine ureteroscopy (URS) is safe.
  • These guidelines are based on limited evidence from small case series.
  • There is a need to further analyze bleeding risks associated with APT in URS procedures.

Purpose of the Study:

  • To analyze bleeding-related complications in patients undergoing ureteroscopy (URS) while on antiplatelet therapy (APT).
  • To evaluate the safety of continuing APT during routine URS procedures.

Main Methods:

  • Retrospective review of 4799 URS procedures performed between June 2009 and February 2016.
  • Identification of patients on APT (aspirin, P2Y12 inhibitors) and assessment of periprocedural complications.
  • Exclusion of patients on concurrent anticoagulants or those undergoing additional non-URS procedures.

Main Results:

  • Out of 4799 URS procedures, 314 (6.5%) involved patients on APT.
  • The overall bleeding-related complication rate was 1.9%, with a significant bleeding rate of 1.6%.
  • No significant difference in bleeding complications was observed between patients who continued APT and those who held it.

Conclusions:

  • Continuing antiplatelet therapy (APT) in patients undergoing routine ureteroscopy (URS) does not appear to increase bleeding-related complications.
  • These findings support the existing American Urological Association (AUA) guidelines regarding APT management during URS.
  • The study provides evidence for the safety of continuing APT in this patient population.
Abstract

Keywords:
laserrenal stoneureteroscopyurolithiasisuteroscopy instrumentation

More Related Videos

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

6.1K
Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser07:17

Photoselective Vaporesection of the Prostate via an End-firing Lithium Triborate Crystal Laser

Published on: May 9, 2018

8.5K

Related Concept Videos

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
1.5K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.3K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
453
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
499
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
2.2K
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
986