Penile Girth Enhancement With Polymethylmethacrylate-Based Soft Tissue Fillers

Area of Science:

• Urology
• Aesthetic Medicine
• Biomaterials Science

Background:

• Men seek penile augmentation for various reasons, but many injectable methods pose significant risks.
• Polymethylmethacrylate (PMMA) microspheres, used safely as a dermal filler since 1989, present a potential solution.

Purpose of the Study:

• To evaluate the safety and efficacy of using an approved dermal filler, Polymethylmethacrylate (PMMA) microspheres, for permanent penile girth and length enhancement.

Main Methods:

• The study analyzed data from 729 men who underwent penile augmentation using Metacrill, a PMMA microsphere suspension, between 2007 and the study period.
• Statistical evaluation included data from 729 patients and 203 completed questionnaires.

Main Results:

• Penile girth increased by an average of 3.5 cm (134%), and length increased from 9.8 cm to 10.5 cm.
• Overall patient satisfaction was high (8.7/10), with rare complications (0.4%) related to nodule formation, particularly in uncircumcised patients.

Conclusions:

• Penile augmentation with Polymethylmethacrylate (PMMA) microspheres is a natural, safe, and permanently effective procedure.
• Improved injection techniques and post-implantation care can mitigate complications like nodule formation and irregularities.