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Updated: Mar 17, 2026

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TRAIP regulates replication fork recovery and progression via PCNA

Wanjuan Feng1, Yingying Guo2, Jun Huang3

  • 1School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., China; Centre for Cancer Research, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., China.

Cell Discovery
|July 28, 2016
PubMed
Summary

Researchers identified TRAIP (RNF206) as a novel protein that interacts with PCNA to aid DNA replication fork recovery during cellular stress. This discovery highlights TRAIP-PCNA interactions in maintaining genome stability.

Keywords:
DNA damagePCNARNF206TRAIPhydroxyureareplication

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