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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
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Headache in Behcet's disease: types and characteristics.

Maryam Moghaddassi1, Mansoureh Togha2, Farhad Shahram1

  • 1Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Springerplus
|July 28, 2016
PubMed
Summary

Headache, particularly tension-type headache, is significantly more prevalent in individuals with Behcet's disease compared to the general population. This finding highlights a potential link between Behcet's disease and specific headache types.

Keywords:
Behcet’s diseaseHeadacheMigraineNon-structural headache

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Area of Science:

  • Neurology
  • Rheumatology
  • Ophthalmology

Background:

  • Behcet's disease is a multisystem inflammatory disorder.
  • Neurological involvement, including headaches, is a common manifestation.
  • Prevalence of Behcet's disease is notably high in Iran.

Purpose of the Study:

  • To compare headache features in Behcet's disease patients versus a healthy control group.
  • To investigate the prevalence and characteristics of headaches in Behcet's disease.
  • To explore potential correlations between headache and disease manifestations.

Main Methods:

  • A case-control study involving 312 Behcet's disease patients and matched healthy controls.
  • Patients were selected from a specialized Behcet's clinic.
  • Standardized questionnaires based on International Headache Society criteria were used.

Main Results:

  • Headache incidence was higher in Behcet's patients (28.3%) than controls (18.6%).
  • Tension-type headache was significantly more frequent in Behcet's patients (12.2%) compared to controls (6.3%).
  • Higher systolic blood pressure was noted in Behcet's patients; a correlation between ophthalmological involvement and headache was observed.

Conclusions:

  • Headache, especially tension-type, is more common in Behcet's disease patients.
  • This increased prevalence may be linked to specific types of headaches associated with Behcet's disease, potentially related to uveitis.