Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

2.1K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.1K
Overview of Systemic Veins01:11

Overview of Systemic Veins

1.6K
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
1.6K
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

2.4K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
2.4K
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

757
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
757
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

3.3K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
3.3K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.2K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The clinical profile of systemic sclerosis without a 'scleroderma pattern' at nailfold capillaroscopy: results from the multicenter SPRING registry of the Italian Society of Rheumatology.

Journal of translational autoimmunity·2026
Same authorSame journal

Tracking interstitial lung disease in systemic sclerosis: integrating lung magnetic resonance imaging into a clinically oriented multimodal follow-up strategy.

Clinical and experimental rheumatology·2026
Same author

Clinical and serological features of triple autoantibody-negative patients with systemic sclerosis: insights from the multicentric SPRING registry of the Italian Society for Rheumatology.

RMD open·2026
Same author

Thyroid disorders in idiopathic inflammatory myopathies: prevalence and related clinical scenarios.

BMC endocrine disorders·2026
Same author

Multiparametric assessment of sarcopenia in systemic sclerosis: prognostic implications and interplay with malnutrition.

Clinical and experimental rheumatology·2026
Same author

The Role of Ultrasound Pleural Irregularities in the Identification of Interstitial Lung Disease in Idiopathic Inflammatory Myopathies.

Journal of personalized medicine·2026

Related Experiment Video

Updated: Mar 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

21.0K

One year in review 2016: systemic sclerosis.

Simone Barsotti1, Chiara Stagnaro2, Anna d'Ascanio2

  • 1Rheumatology Unit, University of Pisa; and Department of Medical Biotechnologies, University of Siena, Italy. simone.barsotti.pisa@gmail.com.

Clinical and Experimental Rheumatology
|July 28, 2016
PubMed
Summary
This summary is machine-generated.

Systemic sclerosis, a rare multi-organ disease, involves complex pathogenesis. This review highlights key advancements in its understanding, diagnosis, and treatment from the past year.

More Related Videos

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.1K
Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
09:24

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Published on: April 15, 2014

18.2K

Related Experiment Videos

Last Updated: Mar 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

21.0K
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.1K
Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
09:24

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Published on: April 15, 2014

18.2K

Area of Science:

  • Rheumatology
  • Immunology
  • Internal Medicine

Background:

  • Systemic sclerosis is a rare autoimmune disease affecting multiple organs.
  • Its complex pathogenesis involves genetic and environmental factors.
  • Significant research is published annually on systemic sclerosis.

Purpose of the Study:

  • To provide an overview of key literature contributions in systemic sclerosis over the last year.
  • To summarize novel insights into pathogenesis, diagnosis, and treatment.
  • To offer a concise update for clinicians and researchers.

Main Methods:

  • Systematic literature search of major databases.
  • Inclusion of high-impact publications from the past 12 months.
  • Expert review and synthesis of relevant studies.

Main Results:

  • Identification of significant advancements in understanding systemic sclerosis pathogenesis.
  • Summary of new diagnostic criteria and biomarkers.
  • Overview of emerging therapeutic strategies and clinical trial outcomes.

Conclusions:

  • The past year has yielded crucial updates in systemic sclerosis research.
  • Continued investigation is vital for improving patient outcomes.
  • This review consolidates essential knowledge for the scientific community.