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Published on: February 15, 2022
[Clinical analysis of aphakic glaucoma following infantile congenital cataract surgery]
1Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Insights
Infantile cataract surgery can lead to aphakic glaucoma in 11.42% of cases, with late-onset open-angle glaucoma being most common. Early-onset angle-closure glaucoma also occurs post-surgery.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Glaucoma Research
Background:
- Congenital cataract surgery in infants is crucial for visual development.
- Aphakic glaucoma is a potential sight-threatening complication following cataract surgery.
- Understanding the incidence and types of aphakic glaucoma is vital for early detection and management.
Purpose of the Study:
- To determine the incidence and timing of aphakic glaucoma after infantile congenital cataract surgery.
- To classify the types of aphakic glaucoma that develop post-operatively.
- To identify risk factors associated with aphakic glaucoma development.
Main Methods:
- Retrospective review of pediatric patients (under 24 months) who underwent congenital cataract surgery.
- Exclusion of patients with pre-existing glaucoma-associated conditions.
- Analysis of surgical methods, age at surgery, and glaucoma development, incidence, and timing.
Main Results:
- 11.42% of patients developed aphakic glaucoma (37 of 324 eyes).
- Early-onset angle-closure glaucoma occurred in 2.78% of eyes (mean 4.2 months post-op).
- Late-onset open-angle glaucoma occurred in 8.64% of eyes (mean 37.5 months post-op), being the most common type.
Conclusions:
- The incidence of aphakic glaucoma following infantile cataract surgery is 11.42%.
- Aphakic glaucoma presents as early-onset angle-closure or late-onset open-angle types.
- Late-onset open-angle glaucoma is the predominant form, with varied onset times post-surgery.
Objective:
To investigate the incidence, occurrence time and types of aphakic glaucoma following infantile congenital cataract surgery.
Methods:
The records of children who underwent surgery for congenital cataract within the first 24 months of life between January 2010 and January 2014 at the First Affiliated Hospital of Zhengzhou University were retrospectively reviewed.Children with preoperative conditions associated with glaucoma were excluded.The following parameters were ascertained: age received cataract surgery, operation method, the incidence, occurrence time and types of glaucoma.
Results:
A total of 205 patients (324 eyes) with an average surgery age of 13.9 months were included, and the mean follow-up time was 47.6 months.The operation method was cataract extraction combined with posterior continuous circular capsulorhexis and anterior vitrectomy.Twenty-nine patients (37 eyes, 11.42%) had subsequent development of aphakic glaucoma, 9 eyes of which (2.78%) developed early onset angle closed glaucoma, and the occurrence time was (4.2±2.6) months after cataract surgery; 28 eyes (8.64%) developed late onset open angle glaucoma, 26 of which was angle open glaucoma, and the rest two was angle closed glaucoma.The occurrence time was (37.5±11.0) months after cataract surgery. Twenty-nine patients (37 eyes) developed aphakic glaucoma had cataract surgery within 2 to 12 months (6.8 months on average). The rest 176 patients (287 eyes) who did not develop glaucoma had cataract surgery at 10 to 24 months (14.1 months on average).
Conclusions:
The incidence of aphakic glaucoma following infantile congenital cataract surgery is 11.42%.Aphakic glaucoma is divided into two types of early onset angle closed glaucoma and late onset open angle glaucoma.The occurence time of glaucoma was 2 months to 64 months after cataract surgery.Late onset open angle glaucoma is the most common type.
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