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Depression and anxiety in patients with hematological malignancies, prevalence, and associated factors

Khadega A Abuelgasim1, Gasmelseed Y Ahmed, Jamilah A Alqahtani

  • 1Department of Oncology, King Abdulaziz Medical City National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia. E-mail. ahmedkh1@ngha.med.sa.

Saudi Medical Journal
|July 29, 2016
PubMed

Insights

Depression and anxiety affect nearly half of hematological cancer patients. Early screening and intervention are crucial for improving both psychological well-being and disease outcomes in these individuals.

Area of Science:

  • Oncology
  • Psychiatry
  • Hematology

Background:

  • Hematological cancers (HC) represent a significant patient population with potential psychological distress.
  • Understanding the prevalence of mental health conditions in HC patients is vital for comprehensive care.

Purpose of the Study:

  • To determine the prevalence of depression and anxiety among patients with hematological cancers.
  • To identify factors associated with depression and anxiety in this patient group.

Main Methods:

  • A cross-sectional survey was conducted with 211 hematological cancer patients at King Abdulaziz Medical City (KAMC) between March 2014 and June 2015.
  • Validated questionnaires, including the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7, were used in face-to-face interviews.
  • Patients with pre-existing depression or generalized anxiety disorder were excluded from the study.

Main Results:

  • Depression was identified in 46.5% of participants, and anxiety was detected in 22.3%.
  • 18.1% of patients experienced both concurrent anxiety and depression.
  • Multiple co-morbidities and a tense home atmosphere were significant predictors of anxiety and depression; however, gender, smoking, income, and active therapy status showed no association.

Conclusions:

  • Depression and anxiety are highly prevalent in hematological cancer patients at KAMC.
  • Healthcare providers should implement routine screening for depression and anxiety in HC patients.
  • Early intervention for these conditions may improve patient outcomes and enhance psychological well-being.
Abstract

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