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Small intestinal perforation in Wegener's granulomatosis
M Tokuda1, N Kurata, H Daikuhara
1First Department of Internal Medicine, Kagawa Medical School, Japan.
The Journal of Rheumatology
|April 1, 1989
Abstract:
Wegener's granulomatosis is a disease characterized by necrotizing vasculitis and granulomatous inflammation. Gastrointestinal (GI) involvement is uncommon in this disorder. Only a few cases of perforation of GI tract have been reported, but vasculitis has not been demonstrated to be a cause of perforation in these cases. We report a case of Wegener's granulomatosis in which a single perforation in the terminal ileum was disclosed on laparotomy and active necrotizing vasculitis was found in the submucosal layer of the resected specimen.