Prenatal genetic counselling for psychiatric disorders

Area of Science:

• Genetics and Psychiatry
• Reproductive Health
• Clinical Psychology

Background:

• Common psychiatric disorders (schizophrenia, bipolar disorder, depression, anxiety, OCD) have complex origins and significant individual/family impact.
• Prenatal diagnosis and counseling are increasingly relevant as families seek to understand genetic risks for offspring.
• The complexity of psychiatric disorders poses challenges for prenatal genetic counseling.

Purpose of the Study:

• To outline the approach to prenatal genetic counseling for psychiatric disorders.
• To assist clinicians in providing comprehensive support to couples seeking this service.
• To share clinical experience from the first specialist service of its kind.

Main Methods:

• Establishment of a specialist prenatal genetic counseling service for psychiatric disorders in Vancouver (2012).
• Provision of counseling to approximately 500 families.
• Clinical experience and case review to inform the counseling process.

Main Results:

• Demonstrated increases in patient empowerment and self-efficacy following genetic counseling.
• Successful application of a structured approach to counseling families with concerns about psychiatric disorders.
• Accumulated experience from counseling ~500 families.

Conclusions:

• Prenatal genetic counseling for psychiatric disorders is feasible and beneficial.
• Specialized services can enhance patient empowerment and self-efficacy.
• The outlined approach can guide clinicians in supporting families facing these complex genetic concerns.