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Outbreaks of human infection caused by pyogenic streptococci of Lancefield groups C and G

A Efstratiou1

  • 1Division of Hospital Infection, Central Public Health Laboratory, London.

Journal of Medical Microbiology
|July 1, 1989
PubMed

Insights

Group C and G streptococci caused 63 probable outbreaks in diverse settings. T-protein antigen identification effectively subdivided these Streptococcus equisimilis strains, aiding in outbreak investigation.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Group C streptococci (Streptococcus equisimilis) and group G streptococci are significant human pathogens.
  • Outbreaks of streptococcal infections can occur in various healthcare and community settings.

Purpose of the Study:

  • To investigate outbreaks caused by group C and G streptococci.
  • To evaluate the utility of T-protein antigen serotyping for strain differentiation.

Main Methods:

  • Analysis of 749 group C and 2348 group G streptococcal strains isolated over six years.
  • Identification of T-protein antigens for serotyping.

Main Results:

  • Sixty-three probable outbreaks were identified across diverse locations including burns units, maternity wards, and community settings.
  • T-protein antigens were identified in 88% of group C and 82% of group G strains.
  • Serotyping based on T-protein antigens proved effective in subdividing the strains.

Conclusions:

  • Group C and G streptococci were responsible for numerous outbreaks in various environments.
  • T-protein antigen serotyping is a valuable tool for characterizing and differentiating Streptococcus equisimilis strains, aiding in epidemiological investigations.

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