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Thickness of Cadaveric Human Lung Tissue.
Edward G Chekan1, John F Cummings2, Isaac Mabe3
1Worldwide Medical & Clinical Affairs, Teleflex, Inc., Morrisville, NC.
Surgical Technology International
|July 29, 2016
Summary
Surgical staple height selection requires knowing lung tissue thickness. This study measured cadaveric human lung tissue, finding significant variation by location and donor, with thinner peripheral tissues and correlations with height and sex.
Area of Science:
- Thoracic Surgery
- Pulmonary Medicine
- Anatomical Research
Background:
- Surgical staple selection depends on tissue thickness and compressibility.
- Accurate measurements of human lung tissue thickness are crucial for surgical planning.
Purpose of the Study:
- To measure the thickness of cadaveric human lung tissue.
- To identify variations in lung tissue thickness across different anatomical locations.
Main Methods:
- Procured whole lungs from 12 donors with specific inclusion criteria.
- Measured anterior-to-posterior tissue thickness at 41 locations using a tissue measuring device (TMD) under constant pressure.
- Ensured measurements were completed within 72 hours of death.
Main Results:
- Cadaveric lung tissue thickness varied significantly by location and within locations, ranging from 1.5 mm to 9.0 mm.
- Peripheral lung locations were generally thinner (mean 4.1 mm) than central locations (mean 5.9 mm).
- Tissue thickness correlated positively with donor height and weight; females had thicker lung tissue than males after adjusting for height.
Conclusions:
- Significant variations in lung tissue thickness exist throughout the lung and within specific locations.
- Peripheral lung tissue is generally thinner than central lung tissue.
- Donor height and sex are factors influencing lung tissue thickness.
