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Text Mining for Drugs and Chemical Compounds: Methods, Tools and Applications
Miguel Vazquez1, Martin Krallinger1, Florian Leitner1
1Centro Nacional de Investigaciones Oncológicas, Biología Computacional y Estructural, Madrid, Spain.
This review explores chemical text mining for drug development, focusing on recognizing chemical entities in scientific literature. It covers methods, applications, and future trends in extracting vital chemical information.
Area of Science:
- Bioinformatics
- Cheminformatics
- Natural Language Processing
Background:
- Drug development relies on understanding chemical properties from vast text data.
- Chemical text mining applications are crucial for extracting this information.
- Challenges remain, particularly in recognizing chemical entities within text.
Purpose of the Study:
- To review strategies for chemical entity recognition in text.
- To discuss other chemical text mining tasks like relationship extraction and structure determination.
- To highlight applications for drug side effects, toxicity, and network analysis.
Main Methods:
- Overview of basic concepts and principles for chemical entity recognition.
- Discussion of technical details with bibliographic references.
- Introduction to existing applications for building text mining pipelines.
Main Results:
- Chemical entity recognition is a key challenge in chemical text mining.
- Various methods and strategies exist for entity recognition and other related tasks.
- Published applications facilitate building pipelines for specific drug development analyses.
Conclusions:
- Chemical text mining is essential for drug development, despite current limitations.
- Advances in entity recognition and related tasks will improve information extraction.
- The field is expected to evolve, offering new possibilities for analyzing chemical data.
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