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[A case report of a giant cell carcinoma of the thyroid]
N Murakami1, Y Kawaura, M Sasaki
11st Dept. of Surgery, Kanazawa Univ. School of Med.
Gan No Rinsho. Japan Journal of Cancer Clinics
|July 1, 1989
Abstract:
Discussed is a case of a giant cell carcinoma that presented a high value of serum thyroglobulin. Histopathologically, this tumor had been diagnosed as being an anaplastic carcinoma that had transformed from a differentiated carcinoma, with calcification that was thought to have occurred from a preceding adenoma. To study the possibility of a malignant transformation, an immunohistochemical study of a specimen confirmed the production of thyroglobulin and vimentin, though the specimen stained negatively for keratin.