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[Plain abdominal film after contrast-enhanced CT; re-evaluation by using iohexol]
Rinsho Hoshasen. Clinical Radiography
|May 1, 1989
Summary
Iohexol, a non-ionic contrast agent, provides excellent urinary tract opacification comparable to iopamidol in enhanced CT scans. This study confirms its utility for comprehensive urinary system evaluation without significant changes in kidney function markers.
Area of Science:
- Radiology
- Medical Imaging
- Contrast Media
Background:
- Enhanced computed tomography (CT) requires effective contrast agents for diagnostic imaging.
- Evaluating the efficacy and safety of novel contrast media is crucial for optimizing diagnostic procedures.
Purpose of the Study:
- To evaluate the diagnostic utility of iohexol, a non-ionic, low-osmotic contrast medium, in abdominal radiography after enhanced CT.
- To compare the opacification characteristics and safety profile of iohexol with iopamidol and diatrizoate.
Main Methods:
- Abdominal radiographs were obtained after enhanced CT using iohexol.
- Comparisons were made with iopamidol (non-ionic, low-osmolality) and diatrizoate (ionic, high-osmolality) contrast media.
- Serum BUN and creatinine levels were monitored before and after iohexol enhancement in 21 patients.
Main Results:
- Iohexol demonstrated good nephrogram opacification and persistent opacification up to 45 minutes post-enhancement, similar to iopamidol.
- Abdominal radiographs after enhanced CT with iohexol proved useful for complete urinary tract observation.
- No significant changes in serum BUN and creatinine were observed after iohexol administration.
Conclusions:
- Iohexol is an effective non-ionic contrast medium for enhanced CT, providing excellent urinary tract visualization.
- Its performance is comparable to iopamidol, making it a suitable option for comprehensive urinary system assessment.
- Iohexol exhibits a favorable safety profile with no significant impact on renal function markers.