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Robotic Enucleation of Esophageal Leiomyoma
Published on: February 20, 2026
313
Robot-assisted minimally invasive esophagectomy.
R van Hillegersberg1, M F J Seesing2, H J F Brenkman2
1Department of Surgical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA, Utrecht, The Netherlands. r.vanhillegersberg@umcutrecht.nl.
Summary
Robot-assisted minimally invasive esophagectomy (RAMIE) offers a safe approach for esophageal cancer, reducing complications and improving quality of life. This technique expands surgical options for advanced tumors and metastatic disease.
Area of Science:
- Surgical Oncology
- Minimally Invasive Surgery
- Gastrointestinal Surgery
Background:
- Esophageal cancer treatment relies on esophagolymphadenectomy, typically via transthoracic approach with two-field lymph node dissection.
- Minimally invasive surgery improves outcomes and quality of life compared to traditional methods.
- Robot-assisted minimally invasive esophagectomy (RAMIE) was developed to enhance thoracoscopic procedures.
Purpose of the Study:
- To evaluate the safety, oncologic outcomes, and morbidity of RAMIE.
- To explore the expanded indications for RAMIE in complex esophageal cancer cases.
Main Methods:
- Utilized a robot-assisted minimally invasive approach for esophagectomy and lymph node dissection.
- Performed gastric conduit reconstruction following the procedure.
Main Results:
- RAMIE demonstrated safety with favorable oncologic results.
- Reduced postoperative morbidity was observed compared to conventional methods.
- RAMIE facilitated curative surgery for T4b tumors, high mediastinal tumors, and post-neoadjuvant lymph node metastases.
Conclusions:
- RAMIE is a safe and effective minimally invasive surgical option for esophageal cancer.
- The robotic approach expands the potential for curative surgical intervention in challenging cases.
- RAMIE improves patient outcomes and quality of life in esophageal cancer management.

