Antibiotics Prophylaxis for Operative Hysteroscopy.

Area of Science:

• Gynecology
• Infectious Diseases
• Surgical Procedures

Background:

• Operative hysteroscopy is a common gynecological procedure.
• Infectious complications can occur following hysteroscopy.
• The use of prophylactic antibiotics is debated.

Purpose of the Study:

• To evaluate the incidence of infectious complications during operative hysteroscopy.
• To determine the effect of prophylactic antibiotic administration on these complications.

Main Methods:

• A multicentric randomized controlled trial involving 180 women.
• Participants received either intravenous cefazolin or no antibiotic prophylaxis.
• Follow-up assessed postoperative fever, endometritis, pain, and other complications.

Main Results:

• No statistically significant difference in postoperative fever, endometritis, pain, or bleeding between groups.
• Similar rates of infectious complications and side effects were observed in both antibiotic and no-treatment groups.
• No significant difference in antibiotic-related side effects like nausea or allergic reactions.

Conclusions:

• Routine antibiotic prophylaxis is not necessary before operative hysteroscopy.
• Current evidence does not support the routine use of antibiotics to prevent infectious complications.