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Related Experiment Videos

[Bladder replacement by enterocystoplasty after total cystectomy].

K Tobisu, Y Tanaka, K Takai

    Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
    |February 1, 1989
    PubMed
    Summary

    Enterocystoplasty using detubularized intestinal segments, including ileum, cecum, and colon, offers effective bladder substitution after total cystectomy. Patients achieved good bladder capacity, continence, and quality of life, with preserved renal function and potency.

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    Randomised phase III study of neoadjuvant chemotherapy with methotrexate, doxorubicin, vinblastine and cisplatin followed by radical cystectomy compared with radical cystectomy alone for muscle-invasive bladder cancer: Japan Clinical Oncology Group Study JCOG0209.

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    Area of Science:

    • Urology
    • Surgical Oncology
    • Gastroenterology

    Context:

    • Total cystectomy for bladder cancer necessitates bladder reconstruction.
    • Enterocystoplasty is a reconstructive surgical technique.
    • Intestinal segments are utilized for bladder augmentation or substitution.

    Purpose:

    • To evaluate the functional outcomes of enterocystoplasty using detubularized intestinal segments for bladder substitution after total cystectomy.
    • To assess vesical capacity, continence, renal function, and quality of life in patients undergoing this procedure.

    Summary:

    • Seven male patients (43-69 years) underwent enterocystoplasty after total cystectomy using detubularized ileum, cecum, and proximal ascending colon (n=5) or ileum/sigmoid-colon (n=2).
    • At 3 months post-operation, 6 patients had vesical capacity ≥300 ml and voided volume ≥200 ml.

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  • Daytime continence was achieved in 6 patients by 3 months, and nighttime continence in 5 patients by 6 months. Renal function and electrolytes remained stable. Potency was preserved in 2 patients. Quality of life was generally good, with one patient requiring self-catheterization.
  • Impact:

    • Enterocystoplasty can restore bladder function and improve quality of life after cystectomy.
    • The shape and pelvic position of the neobladder influence its function.
    • This technique provides a viable option for bladder reconstruction, maintaining renal and sexual health.