Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

815
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
815
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

648
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
648
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

1.4K
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
1.4K
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

7.4K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
7.4K
Synthetic Biology02:55

Synthetic Biology

5.7K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.7K
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

1.2K
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An initial genomic blueprint of the healthy human oesophageal microbiome.

Access microbiology·2023
Same author

Metagenomic investigation of the equine faecal microbiome reveals extensive taxonomic diversity.

PeerJ·2022
Same author

Remarkable genomic diversity among <i>Escherichia</i> isolates recovered from healthy chickens.

PeerJ·2022
Same author

Archaeal and Bacterial Metagenome-Assembled Genome Sequences Derived from Pig Feces.

Microbiology resource announcements·2022
Same author

SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse.

Nature microbiology·2021
Same author

Extensive microbial diversity within the chicken gut microbiome revealed by metagenomics and culture.

PeerJ·2021
Same journal

Mind the Porins: Differential Effects of Porin Knockouts and Overexpression on Glucose and Xylose Uptake and Utilization in Pseudomonas putida.

Microbial biotechnology·2026
Same journal

Coumarins Disrupt Cell-Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa.

Microbial biotechnology·2026
Same journal

Engineering Pseudomonas protegens as a Targeted Antifungal-Effector Delivery Chassis via Heterologous Type III Secretion System Reconstitution.

Microbial biotechnology·2026
Same journal

Adaptive Laboratory Evolution Unlocks Membrane Permeability as a Key Limitation in Long-Chain Alcohol Metabolism by Pseudomonas putida KT2440.

Microbial biotechnology·2026
Same journal

Correction to 'Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics'.

Microbial biotechnology·2026
Same journal

NADPH Dehydrogenase Gene Regulates Energy Distribution and Fatty Acid Metabolism During Fruiting Body Formation in the Filamentous Fungus Podospora anserina.

Microbial biotechnology·2026
See all related articles

Related Experiment Video

Updated: Mar 17, 2026

Investigating Bacterial-Fungal Interactions using Fungal Highway Columns in Diverse Environments and Substrates
05:22

Investigating Bacterial-Fungal Interactions using Fungal Highway Columns in Diverse Environments and Substrates

Published on: January 24, 2025

856

Microbial bioinformatics 2020.

Mark J Pallen1

  • 1Microbiology and Infection Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.

Microbial Biotechnology
|July 30, 2016
PubMed
Summary
This summary is machine-generated.

Microbial bioinformatics is rapidly evolving with new technologies and vast sequence data. Future challenges include adapting taxonomy, integrating genomics into healthcare, and advancing metagenomics for microbial discovery.

More Related Videos

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

19.2K

Related Experiment Videos

Last Updated: Mar 17, 2026

Investigating Bacterial-Fungal Interactions using Fungal Highway Columns in Diverse Environments and Substrates
05:22

Investigating Bacterial-Fungal Interactions using Fungal Highway Columns in Diverse Environments and Substrates

Published on: January 24, 2025

856
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

19.2K

Area of Science:

  • Microbial bioinformatics
  • Genomic data analysis
  • Computational biology

Background:

  • The exponential growth of microbial sequence data presents significant challenges for databases and manual curation.
  • Microbial taxonomy faces adaptation as sequence analysis becomes primary for microorganism discovery.
  • Genome sequencing is becoming standard in clinical and research settings, necessitating user-friendly outputs.

Purpose of the Study:

  • To outline the projected advancements and challenges in microbial bioinformatics for the upcoming decade.
  • To highlight the impact of new technologies and approaches on microbial data analysis.
  • To discuss the evolving role of genomics in healthcare and microbiome research.

Main Methods:

  • Review of current trends and future projections in microbial bioinformatics.
  • Anticipation of technological integration, such as the Internet of Things, in healthcare.
  • Forecasting the shift from molecular barcoding to metagenomics in microbiome studies.

Main Results:

  • Databases and search strategies will be strained by the volume of sequence data.
  • Manual curation will be unsustainable in the era of millions of microbial genomes.
  • Metagenomics will gain prominence over molecular barcoding in microbiome research.
  • Integration of microbial genome sequences with healthcare systems via the Internet of Things is expected.
  • Handheld sequencers and mobile device analysis will become more prevalent.

Conclusions:

  • Microbial bioinformatics will continue to be a dynamic field, driven by sequence data and technological innovation.
  • Adaptability in taxonomy, data interpretation, and workforce training is crucial for future progress.
  • Vigilance is required to prevent misinterpretation and overstatement of microbial sequence data findings.