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Updated: Sep 14, 2026

A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas
Published on: June 5, 2014
[A case of eosinophylic lymphoid granuloma (Kimura's disease) being suspected as cervical tuberculosis]
Abstract:
Although cervical tuberculous lymphadenitis has decreased markedly in accordance with the decline of pulmonary tuberculosis in Japan, a few cases are still found among young people. A thirty-year-old man, being suspected as cervical tuberculous lymphadenitis, underwent a biopsy, and was histologically diagnosed as eosinophilic lymphoid granuloma (Kimura's disease). He had many indurated nodules in the cervical and lower jaw regions (fig. 1). The clinical and biochemical findings were normal except leucocytosis (11,000/mm3) and eosinophilia (19%) in peripheral blood. The histological section showed nodular lesions, composed of collective lymphoid cells with new formation of germinal centers and capillary vessels. Diffuse infiltration of histiocytes, eosinophils and lymphocytes was found through out the lesions. Following daily Predonine medication with decreasing dose from 30 mg to 2.5 mg in one and a half months, the consolidation in the cervical and lower jaw regions became smaller and finally disappeared.
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