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Updated: Mar 17, 2026

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Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
Published on: February 8, 2020
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Monocular Deprivation in Mice
Ya-Tang Li1, Xiao-Lin Chou1, Huizhong Whit Tao1
1Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, USA.
Bio-Protocol
|July 30, 2016
Abstract:
Monocular deprivation is an experimental technique to study the ocular dominance plasticity during critical period (Hubel and Wiesel, 1963). Generally one eye of an animal is sutured during critical period, and the sutured eye is re-opened after either less than three days (short term) or more than three days (long term). Here we describe a detailed protocol for short-term and long-term monocular deprivation in mouse (Ma et al., 2013).

