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Hydroformylation of Olefinic Derivatives of Isosorbide and Isomannide
Piret Villo1, Livia Matt1, Lauri Toom1
1Institute of Technology, University of Tartu , Nooruse 1, 50411 Tartu, Estonia.
Abstract:
The first time application of hydroformylation on olefinic derivatives of isosorbide and isomannide is shown by which a new carbon-carbon bond is formed. Depending on the ligand and reaction conditions used, the C6 regioisomer a can be obtained in 4:1 ratio and excellent yield, whereas C5 isomer b is achieved in almost complete regioselectivity (46:1) and good yield. In the majority of cases only the exo orientation is observed for the obtained aldehydes, and the method is easily applicable also on a 1 g scale.
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