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Related Experiment Video

Updated: Mar 17, 2026

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
07:36

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery

Published on: February 10, 2023

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Biliary Dyskinesia in Children: A Systematic Review.

Neha R Santucci1, Paul E Hyman, Carroll M Harmon

  • 1*Pediatric Gastroenterology, Louisiana State University Health Sciences Center, New Orleans, LA †Pediatric Surgery, Jacobs School of Medicine and Biosciences, Buffalo, NY ‡Louisiana State University Health Sciences Center Libraries, New Orleans, LA §Willis-Knighton Pediatric GI Specialists, Shreveport, LA.

Journal of Pediatric Gastroenterology and Nutrition
|July 30, 2016
PubMed
Summary

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Rising rates of pediatric cholecystectomy for biliary dyskinesia lack supporting evidence. Current diagnostic criteria and gallbladder ejection fraction (GBEF) measures are inconsistent, with varied surgical outcomes and symptom overlap with functional dyspepsia.

Area of Science:

  • Pediatric Gastroenterology
  • Surgical Outcomes Research

Background:

  • Pediatric cholecystectomy rates for biliary dyskinesia are increasing in the US, unlike other nations.
  • Biliary dyskinesia is a recognized functional gallbladder disorder in adults, distinct from pediatric diagnostic criteria often including upper abdominal pain and abnormal gallbladder ejection fraction (GBEF).

Purpose of the Study:

  • To systematically review the literature on pediatric biliary dyskinesia.
  • To evaluate the validity and reliability of diagnostic criteria and GBEF.
  • To assess outcomes following cholecystectomy for this condition in children.

Main Methods:

  • A systematic review adhering to PRISMA guidelines was conducted.
  • Searched seven major databases and screened bibliographies for relevant studies.

Related Experiment Videos

Last Updated: Mar 17, 2026

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
07:36

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery

Published on: February 10, 2023

2.5K
  • Included 31 retrospective chart reviews, noting heterogeneity in diagnostic criteria and GBEF values.
  • Main Results:

    • Significant heterogeneity exists in diagnostic criteria and GBEF thresholds for pediatric biliary dyskinesia.
    • Outcomes after laparoscopic cholecystectomy demonstrated a wide success range (34%-100%), with no consensus on influencing factors.
    • Retrospective study designs limit the interpretation of diagnostic and treatment safety and efficacy.

    Conclusions:

    • There is a lack of consensus on defining symptoms, validating diagnostic tests, and comparing medical versus surgical management for pediatric biliary dyskinesia.
    • Overlapping symptoms with functional dyspepsia complicate diagnosis.
    • Further research, including randomized controlled trials, is needed to establish clear diagnostic and treatment guidelines.