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Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
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Beyond the bull's eye: Recognizing Lyme disease.
Gerard Chaaya1, Juan J Jaller-Char1, Sayed K Ali1
1University of Central Florida College of Medicine, Orlando, and Orlando Veterans Affairs Medical Center, FL, USA.
The Journal of Family Practice
|July 31, 2016
Summary
Lyme disease rashes appear in most cases, but classic bull's-eye lesions are rare. Early recognition and proper treatment are crucial for managing this tick-borne illness effectively.
Area of Science:
- Infectious Diseases
- Dermatology
- Public Health
Background:
- Lyme disease is a significant tick-borne illness with varied dermatological manifestations.
- The characteristic erythema migrans rash is not always present or typical in Lyme disease patients.
Purpose of the Study:
- To describe the prevalence and characteristics of rashes in Lyme disease.
- To educate on identifying Lyme disease rashes beyond the classic bull's-eye lesion.
- To provide guidance on appropriate treatment strategies for Lyme disease.
Main Methods:
- Review of clinical presentations of Lyme disease.
- Analysis of rash morphology in confirmed cases.
- Summary of current treatment guidelines for Lyme disease.
Main Results:
- Rashes are observed in approximately 80% of Lyme disease cases.
- Only about one-third of these rashes exhibit the classic bull's-eye (erythema migrans) morphology.
- Atypical rash presentations are common, necessitating careful clinical evaluation.
Conclusions:
- Lyme disease diagnosis should not solely rely on the presence of a bull's-eye rash.
- Prompt medical attention and treatment are vital for all suspected cases of Lyme disease, regardless of rash appearance.
- Understanding diverse rash presentations improves early detection and management of Lyme disease.

