Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.6K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.6K
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.2K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.2K
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

14.7K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Analysis the Potential Medicinal Substances of Shuangxia Decoction and the Process <i>In Vivo</i> via Mass Spectrometry Technology.

Frontiers in pharmacology·2021
Same author

Radiomics-Based Features for Prediction of Histological Subtypes in Central Lung Cancer.

Frontiers in oncology·2021
Same author

Relationship Between Rheumatoid Arthritis and Pulmonary Function Measures on Spirometry in the UK Biobank.

Arthritis & rheumatology (Hoboken, N.J.)·2021
Same author

Incorporating Guanidinium as Perovskitizer-Cation of Two-Dimensional Metal Halide for Crystal-Array Photodetectors.

Chemistry, an Asian journal·2021
Same author

Guided suturing technique for midface lift through minimal temporal incision.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2021
Same author

Drug-induced liver injury: Oltipraz and C2-ceramide intervene HNF-1α/GSTA1 expression via JNK signaling pathway.

Journal of applied toxicology : JAT·2021
Same journal

Fiber-optic triggering of a two-stage high-current linear transformer driver with laser energy below 100 μJ.

The Review of scientific instruments·2026
Same journal

Optimization of laboratory-scale x-ray absorption spectroscopy (XAS) apparatus for nuclear fuel research.

The Review of scientific instruments·2026
Same journal

Compressed multi-scale entropy and its application in mechanical fault diagnosis.

The Review of scientific instruments·2026
Same journal

Bidirectional drive and multi-resolution adjustment across frequency bands in inertial impact piezoelectric motors via multimodal resonant vibration.

The Review of scientific instruments·2026
Same journal

A magnetic field sensor based on flaky Terfenol-D material and dual fiber grating.

The Review of scientific instruments·2026
Same journal

A novel E-field eight-way cavity combiner for high-power S-band applications.

The Review of scientific instruments·2026
See all related articles

Related Experiment Video

Updated: Mar 17, 2026

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
09:13

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

8.1K

Contributed Review: A new synchronized source solution for coherent Raman scattering microscopy.

Ke Wang1, Yuxin Wang1, Runfu Liang1

  • 1Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.

The Review of Scientific Instruments
|August 1, 2016
PubMed
Summary
This summary is machine-generated.

Synchronized time-lens sources offer a versatile solution for coherent Raman Scattering (CRS) microscopy, enabling label-free imaging of biological and chemical samples with high spectral resolution.

More Related Videos

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.7K
Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

5.0K

Related Experiment Videos

Last Updated: Mar 17, 2026

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
09:13

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering

Published on: July 6, 2019

8.1K
Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.7K
Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

5.0K

Area of Science:

  • Optics and Photonics
  • Biomedical Imaging
  • Spectroscopy

Background:

  • Coherent Raman Scattering (CRS) microscopy enables label-free imaging using endogenous contrast.
  • High spectral resolution in CRS microscopy demands advanced, synchronized picosecond laser sources.
  • Existing laser sources pose significant challenges for CRS microscopy applications.

Purpose of the Study:

  • To review the principles, design, and applications of synchronized time-lens sources for CRS microscopy.
  • To highlight the advantages of time-lens technology in overcoming laser source limitations.
  • To showcase the utility of synchronized time-lens sources in imaging biological and chemical samples.

Main Methods:

  • Utilizing space-time analogy for temporal pulse compression via time-lenses.
  • Employing phase and intensity modulators for picosecond pulse generation.
  • Achieving synchronization by deriving electrical signals from external laser sources, like mode-locked lasers.

Main Results:

  • The time-lens source demonstrates high versatility and compatibility with modulation techniques.
  • Synchronization between the time-lens source and other lasers is physically achievable.
  • Successful application of synchronized time-lens sources in various CRS microscopy modalities.

Conclusions:

  • Synchronized time-lens sources represent a significant advancement for CRS microscopy.
  • This technology facilitates high-resolution, label-free imaging of diverse samples.
  • The versatility and synchronization capabilities position time-lens sources as a key enabler for future CRS microscopy research.