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Updated: Mar 17, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
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Evolving Immunotherapy Approaches for Renal Cell Carcinoma.

Susanna A Curtis1, Justine V Cohen1, Harriet M Kluger2

  • 1Section of Medical Oncology, Department of Medicine, Yale Cancer Center, 333 Cedar Street, PO Box 208028, New Haven, 06510, CT, USA.

Current Oncology Reports
|August 1, 2016
PubMed
Summary

Metastatic renal cell carcinoma (mRCC) remains challenging due to treatment resistance. Immune modulation therapies, including checkpoint inhibitors, offer promising durable survival benefits for patients with mRCC.

Keywords:
Adoptive cell therapyCytokinesImmune checkpoint inhibitorsImmunotherapyRenal cell carcinomaVaccine therapy

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