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PATTERN OF ANTIHYPERTENSIVE THERAPY AMONG DIABETIC HYPERTEN- SIVE PATIENTS IN ZEWDITU MEMORIAL HOSPITAL, ADDIS ABABA

Hailu Abera, Mihret Woldemichael

    Ethiopian Medical Journal
    |August 2, 2016
    PubMed

    Insights

    Diabetic hypertensive patients often receive guideline-consistent drug therapy, but most do not achieve target blood pressure goals. This highlights a gap in managing cardiovascular disease risk in this population.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Pharmacology

    Background:

    • Diabetes mellitus and hypertension are prevalent chronic diseases, significantly increasing cardiovascular disease (CVD) risk.
    • Co-existing hypertension in diabetic patients doubles the risk of CVD, including heart failure, stroke, and renal failure.

    Purpose of the Study:

    • To evaluate the antihypertensive drug prescribing patterns for diabetic hypertensive patients.
    • To assess treatment outcomes regarding blood pressure control and renal function.

    Main Methods:

    • A retrospective review of 382 diabetic-hypertensive patients' medical records.
    • Data collected from August 2014 to January 2015 at Zewditu Memorial Hospital Diabetic Clinic.

    Main Results:

    • Angiotensin-converting enzyme inhibitors (84%) were most common, followed by calcium channel blockers (60%) and beta-blockers (38%).
    • Only 15% of patients achieved target blood pressure (<140/90 mmHg).
    • Renal impairment was noted in 6% of patients with assessed renal function.

    Conclusions:

    • Antihypertensive drug prescribing patterns align with current guidelines.
    • A significant majority of diabetic hypertensive patients failed to reach target blood pressure, indicating a need for improved management strategies.
    Abstract

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