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Filling the (SR)GAP in Excitatory/Inhibitory Balance

Jaichandar Subramanian1, Elly Nedivi1

  • 1Picower Institute for Learning and Memory, Departments of Biology and Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Neuron
|August 2, 2016
PubMed
Summary

SRGAP2A, a protein regulating cell shape, co-regulates excitatory and inhibitory synapse development. This offers a genetic mechanism for maintaining brain excitation-inhibition balance during evolution and speciation.

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