Related Experiment Video
Updated: Mar 17, 2026
10:35
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
18.8K
Adrenocortical Carcinoma Treated by CyberKnife
Yuko Harada1, Shinichiro Miyazaki
1Department of Internal Medicine, Shin-yurigaoka General Hospital, Japan.
Internal Medicine (Tokyo, Japan)
|August 2, 2016
Summary
CyberKnife treatment shows promise for advanced adrenocortical carcinoma. This approach effectively reduced tumor size and hormone levels in a patient with advanced disease.
Area of Science:
- Oncology
- Radiation Oncology
Background:
- Adrenocortical carcinoma is a rare and aggressive endocrine malignancy.
- Advanced stages often present with poor prognosis and limited treatment options.
Observation:
- A 61-year-old female patient with large adrenocortical carcinoma and pulmonary tumor emboli received CyberKnife treatment.
- Positron emission tomography (PET) scans were utilized for follow-up assessment.
Findings:
- CyberKnife treatment led to a significant decrease in fluorodeoxyglucose (FDG) uptake in all treated tumors.
- Hormone levels associated with the adrenocortical carcinoma also decreased post-treatment.
- The patient's condition indicated a positive response to the non-operative CyberKnife intervention.
Implications:
- CyberKnife presents a potentially safe and effective therapeutic option for unresectable or advanced adrenocortical carcinoma.
- Further research is warranted to establish CyberKnife's role in the management of this rare cancer.
Related Concept Videos
02:56Treatment Resistent Cancers
1.5K
1.5K
02:56Treatment Resistant Cancers
3.9K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.9K
02:49Cancer Therapies
10.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.6K
02:49Cancer Therapies
2.9K
2.9K
02:57Targeted Cancer Therapies
9.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
9.1K
02:57Targeted Cancer Therapies
1.7K
1.7K