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Updated: Mar 17, 2026

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
Published on: October 9, 2018
Obtaining consensus regarding international transplantation continues to be difficult for pediatric centers in the
Angela Lorts1,2, Thomas D Ryan1, Armand H Matheny Antommaria3
1The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Abstract:
Organ transplant is life-saving and any given organ may be valuable to a multitude of potential recipients. An allocation system must be used to reconcile the difference between supply and demand, and this system must take into account the impact that accepting international patients may have on the local system. The principles for allocation must be clear, equitable, provide utility and must be monitored so as to maintain public trust. The impact of the system on metrics deemed to be critical must be measured. Finally, strategies must take into account the local culture, size of the region to be supported, the number and experience of transplant centers, and the resources of the healthcare delivery system. Our focus is on the United States, recognizing that strategies and challenges may vary across countries.
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