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Updated: Mar 17, 2026

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
Published on: August 12, 2018
Modeling and Simulations in Time Domain of a Stimulation Set-up for Cortical Applications
Michael Schweigmann1, Frank Kirchhoff2, Klaus P Koch3
1Department of Electrical Engineering, Trier University of applied Sciences, Trier, Germany; Department of Molecular Physiology, School of Medicine, University of Saarland, Homburg, Germany.
Abstract:
Electrical stimulation is used for example to treat neuronal disorders and depression with deep brain stimulation or transcranial electrical stimulation. Depending on the application, different electrodes are used and thus different electrical characteristics exist, which have to be handled by the stimulator. Without a measuring device the user would have to rely on the stimulator being able to deliver the needed stimulation signal. Therefore, the objective of this paper is to present a method to increase the level of confidence with characterization and modelling of the electrical behavior by using the example of one channel of our stimulation device for experimental use. In several simulation studies with an electrode model with values in a typical range for cortical applications the influence of the load onto the stimulator and the possibility to pre-estimate measuring signals in complex networks are shown.

