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Chronic kidney disease in children
Francesca Becherucci1, Rosa Maria Roperto1, Marco Materassi1
1Nephrology and Dialysis Unit , Meyer Children's Hospital , Florence , Italy.
Insights
Pediatric chronic kidney disease (CKD) presents unique challenges and long-term health impacts. Early diagnosis and tailored treatments are crucial for optimizing outcomes and adult life transitions.
Area of Science:
- Pediatric Nephrology
- Chronic Kidney Disease (CKD) Pathophysiology
- Public Health
Background:
- Chronic kidney disease (CKD) is a significant global health concern.
- While less common in children, pediatric CKD has severe long-term consequences.
- Pediatric CKD exhibits distinct characteristics, potentially warranting separate classification.
Purpose of the Study:
- To review the unique aspects of pediatric CKD.
- To discuss the etiology, clinical features, and treatment of childhood CKD.
- To highlight factors impacting long-term health and adult transition.
Main Methods:
- Literature review focusing on pediatric CKD.
- Analysis of disease etiology and clinical manifestations in children.
- Examination of treatment strategies and long-term outcomes.
Main Results:
- Pediatric CKD has specific etiologies and clinical presentations.
- Cardiovascular complications in childhood CKD significantly affect adult health.
- Early and appropriate management is vital for long-term patient well-being.
Conclusions:
- Childhood-onset CKD requires specialized attention due to its unique features.
- Effective management strategies are essential for optimizing health outcomes.
- Transitioning care to adult nephrology services is critical for sustained health.
Abstract:
Chronic kidney disease (CKD) is a major health problem worldwide. Although relatively uncommon in children, it can be a devastating illness with many long-term consequences. CKD presents unique features in childhood and may be considered, at least in part, as a stand-alone nosologic entity. Moreover, some typical features of paediatric CKD, such as the disease aetiology or cardiovascular complications, will not only influence the child's health, but also have long-term impact on the life of the adult that they will become. In this review we will focus on the unique issues of paediatric CKD, in terms of aetiology, clinical features and treatment. In addition, we will discuss factors related to CKD that start during childhood and require appropriate treatments in order to optimize health outcomes and transition to nephrologist management in adult life.
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