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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Nephrons01:10

Nephrons

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The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
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Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Acute Kidney Injury III: Clinical Manifestations01:29

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

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Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
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Chronic kidney disease in children.

Francesca Becherucci1, Rosa Maria Roperto1, Marco Materassi1

  • 1Nephrology and Dialysis Unit , Meyer Children's Hospital , Florence , Italy.

Clinical Kidney Journal
|August 2, 2016
PubMed
Summary

Pediatric chronic kidney disease (CKD) presents unique challenges and long-term health impacts. Early diagnosis and tailored treatments are crucial for optimizing outcomes and adult life transitions.

Keywords:
CKDESRDchronic renal failurechronic renal insufficiencypaediatrics

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Area of Science:

  • Pediatric Nephrology
  • Chronic Kidney Disease (CKD) Pathophysiology
  • Public Health

Background:

  • Chronic kidney disease (CKD) is a significant global health concern.
  • While less common in children, pediatric CKD has severe long-term consequences.
  • Pediatric CKD exhibits distinct characteristics, potentially warranting separate classification.

Purpose of the Study:

  • To review the unique aspects of pediatric CKD.
  • To discuss the etiology, clinical features, and treatment of childhood CKD.
  • To highlight factors impacting long-term health and adult transition.

Main Methods:

  • Literature review focusing on pediatric CKD.
  • Analysis of disease etiology and clinical manifestations in children.
  • Examination of treatment strategies and long-term outcomes.

Main Results:

  • Pediatric CKD has specific etiologies and clinical presentations.
  • Cardiovascular complications in childhood CKD significantly affect adult health.
  • Early and appropriate management is vital for long-term patient well-being.

Conclusions:

  • Childhood-onset CKD requires specialized attention due to its unique features.
  • Effective management strategies are essential for optimizing health outcomes.
  • Transitioning care to adult nephrology services is critical for sustained health.