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In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Management of spinal infections in children with cerebral palsy
A Sebaaly1, R El Rachkidi1, J J Yaacoub1
1Department of orthopedic surgery, Hôtel Dieu de France, university hospital, faculty of medicine, Saint Joseph university, Mount Lebanon, Alfred Naccache street, Achrafieh, 166830 Beirut, Lebanon.
Insights
Cerebral palsy patients undergoing spinal surgery for scoliosis face higher surgical site infection risks. This review explores infection causes and proposes a treatment algorithm for better patient outcomes.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Pediatric Neurology
Background:
- Cerebral palsy (CP) patients with scoliosis undergoing posterior spinal instrumentation have a higher risk of surgical site infection (SSI) compared to those with idiopathic scoliosis.
- Various organisms can cause SSIs in this population.
- Identified risk factors encompass patient-specific characteristics, nutritional status, and surgical factors.
Purpose of the Study:
- To review the pathophysiology of surgical site infection in cerebral palsy patients with scoliosis.
- To propose a treatment algorithm for surgical site infection in this patient group.
Main Methods:
- Comprehensive literature review of current research on SSIs in CP patients with scoliosis.
- Analysis of personal clinical experience with managing these infections.
- Development of a treatment algorithm based on evidence and experience.
Main Results:
- Detailed examination of the mechanisms leading to SSIs in this high-risk population.
- Identification of key contributing factors to infection development.
- Outline of a structured approach to surgical site infection management.
Conclusions:
- Surgical site infection is a significant complication in cerebral palsy patients with scoliosis requiring spinal instrumentation.
- A clear understanding of pathophysiology and risk factors is crucial for prevention and management.
- The proposed treatment algorithm aims to guide clinicians in effectively managing SSIs in this vulnerable patient group.
Abstract:
Cerebral palsy patients who undergo posterior spinal instrumentation for scoliosis are at a greater risk of surgical site infection compared to adolescents with idiopathic scoliosis. Many infecting organisms are reported. Risk factors include patients' specific factors, nutritional status as well as surgery related factors. Although surgical management is still controversial, it is always based on irrigation and debridement followed or not by implant removal. The purpose of this paper is to review the pathophysiology of surgical site infection in this patient population and to propose a treatment algorithm, based on a thorough review of the current literature and personal experience.
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