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Atrial Electromechanical Coupling in Patients with Lichen Planus
Mehmet Yaman1, Uğur Arslan1, Osman Beton2
1Department of Cardiology, Samsun Education and Research Hospital, Samsun, Turkey.
Lichen planus patients exhibit impaired atrial electromechanical coupling, indicated by increased P wave dispersion and delays. These findings correlate with elevated high-sensitivity C-reactive protein levels, suggesting an inflammatory link.
Area of Science:
- Cardiology
- Dermatology
- Internal Medicine
Background:
- Lichen planus is a chronic inflammatory condition.
- It may disrupt atrial electromechanical coupling, increasing atrial fibrillation risk.
Purpose of the Study:
- To assess atrial electromechanical delay in lichen planus patients.
- Utilized electrocardiography (ECG) and echocardiography for evaluation.
Main Methods:
- Cross-sectional case-control study with 72 lichen planus patients and 70 matched controls.
- Measured P wave dispersion via ECG.
- Assessed inter- and intra-atrial electromechanical delays using transthoracic echocardiography.
Main Results:
- Lichen planus patients showed significantly higher P-wave dispersion (ECG).
- Prolonged intra- and interatrial electromechanical delays were observed in lichen planus patients.
- These delays correlated significantly with high-sensitivity C-reactive protein (hsCRP) levels.
Conclusions:
- Atrial electromechanical coupling is impaired in lichen planus.
- Impairment is linked to elevated hsCRP levels, indicating an inflammatory association.
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