Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Memory alterations over a football season are dependent on athlete position-type and prior concussion history.

Brain injury·2026

Same author

Can We Pioneer a Traumatic Brain Injury Blood Test in Trauma Patients Being Considered for Computed Tomography Scanning of the Head?

Annals of emergency medicine·2026

Same author

Macular Pigment Carotenoid Supplementation for the Preservation of Visual Structure and Function Following a Collegiate Rugby Season.

Eye and brain·2025

Same author

Biofluid Biomarkers of Acute Traumatic Spinal Cord Injury: A Systematic Review.

Journal of neurotrauma·2025

Same author

Glymphatic system dysfunction associated with player position in collegiate American football players: A DTI-ALPS study.

Neuroimage. Reports·2025

Same author

Clinical Studies Examining Intrathecal Drainage for Acute Traumatic Spinal Cord Injury: A Living Systematic Review.

Neurotrauma reports·2025

Search research articles

Related Experiment Video

Updated: Mar 16, 2026

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Published on: April 27, 2021

Potential Blood-based Biomarkers for Concussion.

¹Department of Emergency Medicine, Orlando Regional Medical Center, Orlando, FL.

Sports Medicine and Arthroscopy Review

|August 3, 2016

Summary

Biomarkers for sports concussion are crucial for early detection and management, aiding in the prevention of long-term brain injury. Validated blood tests could revolutionize concussion diagnosis and treatment across sports and military settings.

More Related Videos

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

Related Experiment Videos

Last Updated: Mar 16, 2026

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Objectively Assessing Sports Concussion Utilizing Visual Evoked Potentials

Published on: April 27, 2021

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion

Published on: September 25, 2014

Area of Science:

Sports Medicine
Neurology
Biomarker Research

Background:

Research into sports concussion biomarkers has significantly advanced understanding of sports-related brain injuries.
Most studies on concussion biomarkers have been published since 2000.
Early diagnostic and prognostic tools are vital for preventing chronic traumatic encephalopathy and long-term consequences, especially in athletes and military personnel.

Purpose of the Study:

To highlight the growing importance of biomarkers in sports concussion management.
To explore the potential roles of validated blood-based biomarkers in diagnosing, assessing severity, and monitoring recovery from concussion.
To discuss the integration of biomarkers into return-to-activity guidelines and treatment efficacy assessments.

Main Methods:

Systematic review of clinical studies on sports-related concussion biomarkers.
Analysis of the timeline and publication trends of concussion biomarker research.
Discussion of potential applications based on current understanding and future validation.

Main Results:

A substantial body of research on sports concussion biomarkers has emerged, primarily post-2000.
Validated blood-based biomarkers could enable on-field, in-clinic, and monitoring applications.
Potential uses include point-of-care testing, severity assessment, neuroimaging screening, and treatment evaluation.

Conclusions:

Biomarkers are essential for early and tailored management of sports concussions.
Validated biomarkers offer significant potential to improve diagnostic accuracy, treatment strategies, and patient outcomes.
The integration of biomarkers into clinical practice and return-to-activity protocols is a key future direction.