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Updated: Mar 16, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
VENOUS ULCER--A NEW THERAPEUTIC APPROACH
Trophic leg ulcers, often caused by chronic venous insufficiency, affect 1-2% of the population. Minimally invasive treatments like ultrasound-guided sclerotherapy offer improved outcomes over traditional surgical methods.
Area of Science:
- Vascular Surgery
- Dermatology
- Phlebology
Background:
- Trophic leg ulcers represent a significant health burden, impacting 1-2% of the population, particularly the elderly.
- Chronic venous insufficiency, characterized by saphenous system reflux and calf perforator vein incompetence, is the primary etiology.
- Traditional surgical interventions, like Linton's operation, are largely abandoned due to significant morbidity and poor long-term results.
Purpose of the Study:
- To review the current minimally invasive treatment options for trophic leg ulcers.
- To highlight the advantages of newer techniques in managing chronic venous insufficiency-related ulcers.
- To compare the efficacy and patient outcomes of minimally invasive procedures versus historical surgical approaches.
Main Methods:
- Review of current literature on minimally invasive treatments for trophic leg ulcers.
- Focus on ultrasound-guided sclerotherapy as a primary example of modern interventions.
- Comparison of outcomes including healing time, recurrence rates, and patient comfort.
Main Results:
- Minimally invasive procedures, such as ultrasound-guided sclerotherapy, are effective in closing incompetent perforator veins.
- These techniques offer reduced patient discomfort, fewer complications, and shorter hospital stays compared to traditional surgery.
- Ultrasound guidance enhances precision in targeting incompetent perforator veins.
Conclusions:
- Minimally invasive treatments represent a significant advancement in managing trophic leg ulcers secondary to chronic venous insufficiency.
- Ultrasound-guided sclerotherapy provides a safe and effective alternative to historical surgical interventions.
- Further research into optimizing minimally invasive techniques can improve healing rates and reduce ulcer recurrence.
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