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Risk Factors for Central line associated Bloodstream Infections
Shilpa Tomar1, Rakesh Lodha, Bimal Das
1Department of Microbiology and *Pediatric Intensive Care Unit, AIIMS, New Delhi, India. Correspondence to: Dr Arti Kapil, Professor, Department of Microbiology, All India Institute of Medical Sciences, New Delhi 110 029, India. akapilmicro@gmail.com.
Insights
Surveillance of central line-associated bloodstream infections (CLABSIs) in a Pediatric Intensive Care Unit (PICU) identified key risk factors. Interventions targeting line manipulation are crucial for preventing these infections.
Area of Science:
- Pediatric Intensive Care
- Infectious Disease Epidemiology
Background:
- Central line-associated bloodstream infections (CLABSIs) are a significant concern in pediatric intensive care units (PICUs).
- Effective surveillance and identification of risk factors are essential for developing targeted prevention strategies.
Purpose of the Study:
- To conduct surveillance of CLABSIs within a PICU setting.
- To identify and analyze associated risk factors contributing to CLABSIs in pediatric patients.
Main Methods:
- A prospective study was conducted over 1.5 years in the PICU.
- Infections were identified following CDC definitions.
- Associated risk factors were systematically recorded and analyzed.
Main Results:
- A total of 265 children with central lines were enrolled.
- 13 cases of CLABSIs were identified, resulting in an incidence density of 5.03 per 1000 central line days.
- Significant risk factors included central line manipulation, particularly with triple-lumen catheters, and frequent line access.
Conclusions:
- CLABSIs are preventable primary bacteremias.
- Evidence-based intervention strategies are necessary for developing future prevention protocols.
- Targeted interventions focusing on reducing line manipulation and access frequency can mitigate CLABSI rates.
Objective:
To carry out surveillance of central line associated bloodstream infections in a Pediatric intensive care unit (PICU) and determine associated risk factors.
Methods:
This prospective study was conducted over 1.5 years in the PICU. CDC definitions for these infections were followed and associated risk factors were identified.
Results:
Of 265 enrolled children with central line, 13 developed blood stream infections (incidence density 5.03/1000 central line days). Significant risk factors included changing the central-line, especially triple lumen, and frequently accessing the central line.
Conclusion:
Central line associated bloodstream infections are preventable primary bacteremias and intervention strategies for prevention should be based on evidence generated to devise future protocols.
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