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Updated: Mar 16, 2026

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
[Chest pain at 32 weeks' gestation: pregnancy-related spontaneous coronary artery dissection]
A Schmutz1, P Quaas2, S Grundmann3
1Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Freiburg i. Brsg., Hugstetter Str. 55, 79106, Freiburg, Deutschland. axel.schmutz@uniklinik-freiburg.de.
Abstract:
A 32-year-old woman at 32 weeks gestation presented with cardiac arrest due to ventricular tachycardia following acute chest pain at home. After immediate defibrillation with return of spontaneous circulation (ROSC), an ST segment elevation myocardial infarction due to coronary artery dissection was confirmed. Two drug-eluting stents were implanted and she was placed on dual antiplatelet therapy (DAPT). The echocardiogram showed akinesis of the apex and anterior wall. The patients risk for stent thrombosis was considered high and therefore DAPT was continued until cesarean section at 35 weeks gestation. Intraoperatively she received two units of packed red blood cells, one platelet concentrate, 4 g fibrinogen and 2 g tranexamic acid. Left ventricular ejection fraction deteriorated 8 days after delivery and the patient developed congestive heart failure.
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