Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

453
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
453
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

325
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
325
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

526
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
526
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

452
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
452
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

391
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
391
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The First Report of <i>mcr-1</i>-Carrying <i>Escherichia coli</i> Originating from Animals in Serbia.

Antibiotics (Basel, Switzerland)Ā·2021
Same author

Provisional Use of CLSI-Approved Quality Control Strains for Antimicrobial Susceptibility Testing of <i>Mycoplasma</i> (<i>'Mesomycoplasma'</i>) <i>hyorhinis</i>.

MicroorganismsĀ·2021
Same author

Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs.

The Veterinary recordĀ·2021
Same author

A New Tool to Assess Quality of Life in Patients with Idiopathic Pulmonary Fibrosis or Non-specific Interstitial Pneumonia.

Pneumologie (Stuttgart, Germany)Ā·2021
Same author

Emergence of a <i>tet</i>(M) Variant Conferring Resistance to Tigecycline in <i>Streptococcus suis</i>.

Frontiers in veterinary scienceĀ·2021
Same author

Detection of a NDM-5-producing Klebsiella pneumoniae sequence type 340 (CG258) high-risk clone in swine.

Veterinary microbiologyĀ·2021

Related Experiment Video

Updated: Mar 16, 2026

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

3.5K

Prophylactic Antibiotic Therapy for Preventing Poststroke Infection.

Stefan Schwarz1

  • 1Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany. stefan.schwarz@zi-mannheim.de.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics
|August 4, 2016
PubMed
Summary

Preventive antibiotic therapy in acute stroke lowers infection rates but does not improve patient outcomes. Current evidence does not support its use for acute stroke patients.

Keywords:
Acute strokeAntibiotic prophylaxisFeverInfectionPneumonia

More Related Videos

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.5K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K

Related Experiment Videos

Last Updated: Mar 16, 2026

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
07:34

Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research

Published on: December 15, 2023

3.5K
Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.5K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Clinical Trials

Background:

  • Infections, particularly pneumonia, are frequent complications following acute stroke.
  • These infections are linked to poorer neurological and functional recovery.
  • Stroke-induced immunodeficiency is a key factor in post-stroke infections.

Purpose of the Study:

  • To evaluate the efficacy of preventive antibiotic therapy in reducing infections and improving outcomes in acute stroke patients.

Main Methods:

  • Review of recent large, open-label, controlled trials on preventive antibiotic therapy in acute stroke.
  • Analysis of studies including the "Preventive Antibiotics in Stroke Study" and the STROKE-INF study.

Main Results:

  • Preventive antibiotics reduced infection rates in one study but did not impact clinical outcomes.
  • In patients with dysphagia, antibiotic therapy did not decrease pneumonia incidence or improve prognosis.
  • Two large trials failed to show improved clinical outcomes with preventive antibiotic therapy in stroke units.

Conclusions:

  • Preventive antibiotic therapy is not currently recommended for acute stroke patients.
  • While it may reduce infection rates, it does not consistently improve clinical outcomes.
  • Further research may be needed, but current evidence is insufficient to support this strategy.