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Updated: Mar 16, 2026

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Vascular age calculation and equivalent risk factors in HIV-infected patients obtained from the D:A:D risk equation

Jose I Cuende1, Adriana Saltijeral2, Vicente Estrada3

  • 1Internal Medicine Department, Complejo Asistencial Universitario de Palencia, Spain.

European Journal of Preventive Cardiology
|August 4, 2016
PubMed

Insights

Vascular age, a measure of cardiovascular system health, can now be calculated for HIV patients using the D:A:D equation. This tool aids in understanding and managing cardiovascular risk in this population.

Area of Science:

  • Cardiovascular Health
  • HIV Medicine
  • Risk Assessment

Background:

  • Vascular age estimates cardiovascular system health.
  • The Data Collection on Adverse Effects of Anti-HIV Drugs (D:A:D) Study created a cardiovascular risk equation for HIV-infected patients.
  • This equation incorporates antiretroviral therapy and traditional cardiovascular risk factors.

Purpose of the Study:

  • To determine vascular age in HIV-infected patients using the D:A:D equation.
  • To apply a novel cardiovascular risk assessment tool to a specific patient population.

Main Methods:

  • Vascular age was calculated using the established D:A:D equation.
  • The Poisson regression model, an exponential model, was employed.
  • This model matches patient risk factors to those of a controlled subject.

Main Results:

  • An equation for calculating vascular age in patients was derived.
  • A table for simplified vascular age calculation was created.
  • A table of cardiovascular risk equivalents was developed.

Conclusions:

  • Vascular age, derived from Framingham risk tables, can be calculated using scales like D:A:D for HIV patients.
  • Calculating vascular age in HIV patients may improve communication of cardiovascular risk.
  • This method could enhance the management of modifiable cardiovascular risk factors in HIV patients.
Abstract

Keywords:
D:A:D equationHIVvascular age

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