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Related Concept Videos

Documentation of Nursing Diagnosis01:10

Documentation of Nursing Diagnosis

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The nurse documents nursing diagnoses and enters them into the patient record. The identified patient's nursing diagnosis is either written out with a plan of care or entered into the electronic health record.
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Formulating and Validating Nursing Diagnosis II01:25

Formulating and Validating Nursing Diagnosis II

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Nursing diagnoses represent a problem validated by major defining characteristics. There are four categories of nursing diagnoses: problem-focused, risk, health promotion or wellness, and syndrome. The anatomy of a nursing diagnosis includes three components: problem statement or diagnostic label, defining characteristics, and related factors.
Risk nursing diagnoses represent clinical judgments of an individual, family, or community more vulnerable to developing the health problem than others...
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Current Trends in Nursing II01:30

Current Trends in Nursing II

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Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
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Formulating and Validating Nursing Diagnosis I01:26

Formulating and Validating Nursing Diagnosis I

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A nursing diagnosis is written when the nurse recognizes a cluster of essential patient data indicating health problems treated with independent nursing interventions. The standardized terminologies of a nursing diagnosis help nurses identify and treat patients' problems. Every electronic health record that uses nursing diagnosis must employ standard diagnostic terminology. Developing an efficient, individualized care plan begins with accurate nursing diagnoses.
There are thirteen domains...
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Nursing Diagnosis01:22

Nursing Diagnosis

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Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...
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An in vitro model to mimic the thrombotic occlusion of small vessels in catastrophic antiphospholipid syndrome (CAPS).

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Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
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APS - Diagnostics and challenges for the future.

V Pengo1, E Bison1, G Zoppellaro1

  • 1Department of Cardiac, Thoracic and Vascular Sciences, Clinical Cardiology, Thrombosis Centre, Padova, Italy; Department of Medicine, Division of Rheumatology, University of Padova Medical School, Padova, Italy.

Autoimmunity Reviews
|August 4, 2016
PubMed
Summary
This summary is machine-generated.

Diagnosing antiphospholipid syndrome (APS) relies on detecting antiphospholipid (aPL) antibodies. New guidelines and antibody tests, like those for β2-Glycoprotein I, improve diagnosis and risk assessment for APS patients.

Keywords:
Lupus AnticoagulantPhospholipidsRussell Viper VenomThrombosiscardiolipininhibitorsyndromeß2-glycoprotein 1

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Area of Science:

  • Immunology
  • Hematology
  • Rheumatology

Background:

  • Antiphospholipid syndrome (APS) diagnosis primarily relies on detecting antiphospholipid (aPL) antibodies.
  • Recent guidelines have advanced the standardization of coagulation and immunological tests for aPL detection.
  • Prospective studies highlight the clinical significance of aPL profiles, identifying triple positivity as a high-risk pattern.

Purpose of the Study:

  • To review current diagnostic approaches for antiphospholipid syndrome (APS).
  • To discuss advancements in antiphospholipid antibody testing, including novel targets.
  • To identify remaining challenges in APS pathophysiology and treatment.

Main Methods:

  • Literature review of recent guidelines and cohort studies on antiphospholipid syndrome (APS).
  • Analysis of diagnostic advancements, including standardized coagulation and immunological tests.
  • Evaluation of emerging antiphospholipid antibody assays, specifically anti-β2-Glycoprotein I domain antibodies.

Main Results:

  • Standardization of coagulation and immunological tests has progressed, enhancing aPL detection.
  • Triple positivity for aPL antibodies is confirmed as a high-risk indicator in APS.
  • Antibodies targeting domain 1 and domains 4/5 of β2-Glycoprotein I (β2GP1) show diagnostic promise.

Conclusions:

  • Current diagnostic strategies for APS are improving with standardized testing and risk stratification.
  • Novel antibody targets, such as anti-β2GP1 antibodies, offer enhanced diagnostic accuracy.
  • Further research is needed to elucidate β2GP1 function, APS pathophysiology, and optimize treatment, particularly for catastrophic APS.