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Related Experiment Video

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Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
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Quantitative analysis of lymph nodes in neck dissection specimens. Morphologic study.

Fábio de Aquino Capelli1, Vitor Ribeiro Paes2, Mariangela Marinheiro Machado3

  • 1MD, Department of Head and Neck Surgery, School of Medicine, Universidade de São Paulo (USP), Sao Paulo-SP, Brazil. Analysis of data, manuscript writing, design and supervise all phases of the study.

Acta Cirurgica Brasileira
|August 4, 2016
PubMed
Summary
This summary is machine-generated.

This study quantifies lymph node yield in modified radical neck dissection, establishing a benchmark for minimum nodal recovery and detailing counts per anatomical level for surgical practice.

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Area of Science:

  • Anatomy
  • Surgical Oncology

Background:

  • Modified radical neck dissection (MRND) is a critical oncologic procedure.
  • Accurate lymph node (LN) enumeration is essential for staging and treatment assessment.

Purpose of the Study:

  • To determine the precise number of lymph nodes harvested during modified radical neck dissection.
  • To establish a quantitative parameter for nodal yield in MRND.

Main Methods:

  • A cross-sectional anatomical study.
  • Involved analysis of 56 modified radical neck dissections from 28 non-preserved cadavers.

Main Results:

  • Mean lymph node counts per level: IA (1.5), IB (2.5), IIA (7.2), IIB (6.5), III (6.6), IV (8.6), V (11).
  • Total mean lymph node yield was 43.8 per dissection (95% CI: 40.3–47.4).

Conclusions:

  • The study provides a reference for minimum recommended nodal yield in MRND.
  • Quantifies lymph node distribution across anatomical levels for clinical application.