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Updated: Mar 16, 2026
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
Quantitative analysis of lymph nodes in neck dissection specimens. Morphologic study
Fábio de Aquino Capelli1, Vitor Ribeiro Paes2, Mariangela Marinheiro Machado3
1MD, Department of Head and Neck Surgery, School of Medicine, Universidade de São Paulo (USP), Sao Paulo-SP, Brazil. Analysis of data, manuscript writing, design and supervise all phases of the study.
Purpose:
To quantify the amount of lymph nodes harvested in modified radical neck dissection.
Methods:
Cross-sectional anatomical study conducted in 28 non-preserved cadavers.
Results:
The mean number of lymph nodes found in each nodal level of the 56 modified radical neck dissections performed were: level IA - 1.5 (95% CI: 1.1 - 1.8), level IB - 2.5 (95% CI: 2.1 - 2.9), level IIA - 7.2 (95% CI: 6.0 - 8.5), IIB level - 6.5 (95% CI: 5.5 - 7.4), level III - 6.6 (95% CI: 5.7 - 7.4), level IV - 8.6 (95% CI: 7.1 - 10.1), level V - 11 (95% CI: 9.2 - 12.7), totalizing 43.8 lymph nodes (95% CI: 40.3 - 47.4).
Conclusion:
The results defined a parameter in relation to the minimum recommended nodal yield in a modified radical neck dissection, as well as the number of lymph nodes in each level of this dissection, performed in clinical practice.
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