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A COMPARATIVE STUDY OF THE ANALGESIC EFFECT OF INTRAVENOUS PETHIDINE VS. KETOROLAC AFTER INGUINAL HERNIA SURGERY IN

Hamid Hajigholam Saryazdi, Omid Aghadavoudi, Amir Shafa

    Middle East Journal of Anaesthesiology
    |August 5, 2016
    PubMed

    Insights

    Ketorolac was more effective than pethidine in controlling postoperative pain in children undergoing inguinal hernia surgery. Ketorolac demonstrated lower pain scores and reduced pain variation, indicating superior pain management.

    Area of Science:

    • Pediatric Surgery
    • Anesthesiology
    • Pharmacology

    Background:

    • Postoperative pain management is crucial for patient recovery, preventing complications like prolonged hospitalization and increased morbidity.
    • Non-steroidal anti-inflammatory drugs (NSAIDs) and narcotics are common analgesic options.
    • Ketorolac (NSAID) and pethidine (narcotic) are frequently used for pain control.

    Purpose of the Study:

    • To compare the efficacy of ketorolac and pethidine in managing postoperative pain in children.
    • To evaluate pain control after inguinal herniorrhaphy in pediatric patients aged 1-12 years.

    Main Methods:

    • A randomized study involving 66 children undergoing inguinal herniorrhaphy.
    • Children were divided into two groups: one receiving ketorolac (0.5 mg/kg) and the other pethidine (1 mg/kg) during extubation.
    • Postoperative pain was assessed using the Wong Baker pain scale for 24 hours.

    Main Results:

    • Ketorolac group showed significantly lower mean pain scores at 1 hour (3.88 vs. 5.06) and 2 hours (3.55 vs. 4.48) post-surgery (P < 0.001 and P = 0.006, respectively).
    • The variation in pain intensity was statistically lower in the ketorolac group compared to the pethidine group (P = 0.020).

    Conclusions:

    • Ketorolac is more effective than pethidine for postoperative pain control in pediatric inguinal hernia repair.
    • Ketorolac offers superior pain management with less variability compared to pethidine.
    Abstract

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