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Primary pulmonary plasmacytoma: a case report introduction.

Si Nie1, De-Chang Peng2, Hong-Han Gong1

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Area of Science:

  • Oncology
  • Pulmonology
  • Pathology

Background:

  • Extramedullary plasmacytoma is a rare plasma cell neoplasm occurring outside the bone marrow.
  • Primary pulmonary plasmacytoma is an exceptionally rare subtype of extramedullary plasmacytoma.
  • It lacks systemic features of multiple myeloma.

Observation:

  • A 48-year-old male presented with a middle ear tumor.
  • Initial investigations revealed an enlarged left lung hilum on chest X-ray.
  • A subsequent CT scan identified a well-circumscribed solitary pulmonary nodule.

Findings:

  • Pathological biopsy confirmed the diagnosis of isolated pulmonary plasmacytoma.
  • This represents the first reported case of primary pulmonary plasmacytoma presenting as a solitary pulmonary nodule.
  • No lymph node involvement was detected.

Implications:

  • This case expands the clinical spectrum of primary pulmonary plasmacytoma.
  • It underscores the need for thorough differential diagnosis in cases of solitary pulmonary nodules.
  • Further research into the pathogenesis and optimal management of this rare condition is warranted.