[Graduated optimization of fractionation using a 2-component model]

To calculate the optimal conditions for fractionation a two-component multitarget model and a gradual optimizing method were applied for several tumor types (squamous cell carcinoma of skin, adenocarcinoma of mamma) and for critical normal tissue (skin, vessel-stroma). The calculated regimes guarantee a tumor healing without complications with high probability (70-95%). This probability is higher by 10-11% than in computer-based calculation by probit analysis.