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Updated: Mar 16, 2026

Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis
Published on: February 2, 2021
123I-FP-CIT-SPECT in Encephalitis Involving Substantia Nigra
Hubert Tissot1, Solene Frismand, Pierre-Yves Marie
1From the Departments of *Nuclear Medicine, and †Neurology, CHU-Nancy, F-54000, Nancy, France.
Abstract:
I-FP-CIT-SPECT is currently used to detect functional impairment of striatal structures. We report herein a case where I-FP-CIT abnormalities are seemingly related to an encephalitis involving substantia nigra. A few months after a documented encephalitis, a 19-year-old woman experienced a Parkinsonism with a right dominance. There was a reduction in the striatal binding of I-FP-CIT, especially on the left side, in accordance with the right dominance of the Parkinsonism.

