Related Experiment Video
Updated: Mar 16, 2026
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
Autologous collagen induced chondrogenesis (ACIC: Shetty-Kim technique) - A matrix based acellular single stage
Asode Ananthram Shetty1, Seok Jung Kim2, Vishvas Shetty3
1Canterbury Christ Church University, Institute of Medical Sciences, Faculty of Health and Wellbeing, 30 Pembroke Court, Chatham Maritime, Kent ME4 4UF, United Kingdom.
Abstract:
The defects of articular cartilage in the knee joint are a common degenerative disease and currently there are several established techniques to treat this problem, each with their own advantages and shortcomings. Autologous chondrocyte implantation is the current gold standard but the technique is expensive, time-consuming and most versions require two stage procedures and an arthrotomy. Autologous collagen induced chondrogenesis (ACIC) is a single-stage arthroscopic procedure and we developed. This method uses microfracture technique with atelocollagen mixed with fibrin gel to treat articular cartilage defects. We introduce this ACIC techniques and its scientific background.
